8D4X

Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a dimeric form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	E3 ubiquitin-protein ligase UBR5	polymer	2806	310604.6	2	UniProt (O95071) Pfam (PF11547) Pfam (PF00658) Pfam (PF00632) In PDB	Homo sapiens (human)	E3 ubiquitin-protein ligase,HECT domain-containing 1,HECT-type E3 ubiquitin transferase UBR5,Hyperplastic discs protein homolog,hHYD,Progestin-induced protein
2	A, B	ZINC ION	non-polymer		65.4	6	Chemie (ZN)

Sequence modifications

A, B: 1 - 2799 (UniProt: O95071)

PDB	External Database	Details
Asp -6	-	expression tag
Tyr -5	-	expression tag
Lys -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	621209.3
Non-Polymers*	Number of molecules	6
	Total formula weight	392.5
All*	Total formula weight	621601.7

*Water molecules are not included.