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8D3O

Crystal structure of human Apoptosis-Inducing Factor (AIF) complexed with 8-methoxyquinolin-4-amine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BApoptosis-inducing factor 1, mitochondrialpolymer54359470.62UniProt (O95831)
Pfam (PF00070)
Pfam (PF14721)
In PDB
Homo sapiens (human)Programmed cell death protein 8
2DApoptosis-inducing factor (AIF), unidentified helixpolymer7613.71Homo sapiens
3A, B8-methoxyquinolin-4-aminenon-polymer174.22Chemie (QF6)
4A1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5A, BFLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.52Chemie (FAD)
6A, BSULFATE IONnon-polymer96.18Chemie (SO4)
7waterwater18.0144Chemie (HOH)
Sequence modifications
A, B: 78 - 613 (UniProt: O95831)
PDBExternal DatabaseDetails
Met 77-initiating methionine
Leu 614-expression tag
Glu 615-expression tag
Val 616-expression tag
Leu 617-expression tag
Phe 618-expression tag
Gln 619-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight119554.9
Non-Polymers*Number of molecules13
Total formula weight2750.1
All*Total formula weight122305.0
*Water molecules are not included.

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PDB entries from 2024-05-15

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