8D3C

VWF tubule derived from monomeric D1-A1

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	von Willebrand factor	polymer	1469	162301.0	16	UniProt (P04275) Pfam (PF00094) Pfam (PF16164) Pfam (PF00092) Pfam (PF08742) Pfam (PF01826)	Homo sapiens (human)	vWF
2	AA, AD, AE, BD, CC... (B, L, O, I, F...)	CALCIUM ION	non-polymer		40.1	48	Chemie (CA)
3	AB, AC, BA, BB, BC... (E, H, B, O, L...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	80	Chemie (NAG)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 1 - 1464 (UniProt: P04275)

PDB	External Database	Details
-	Arg 760	deletion
Ala 761	Ser 761	engineered mutation
Ser 762	Lys 762	engineered mutation
Ala 763	Arg 763	engineered mutation
Ala 789	Thr 789	variant
Arg 852	Gln 852	variant
Ala 1381	Thr 1381	variant
His 1465	-	expression tag
His 1466	-	expression tag
His 1467	-	expression tag
His 1468	-	expression tag
His 1469	-	expression tag
His 1470	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	2596815.7
Non-Polymers*	Number of molecules	128
	Total formula weight	19620.4
All*	Total formula weight	2616436.1

*Water molecules are not included.