8D2T

Zebrafish MFSD2A isoform B in inward open ligand-free conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Sodium-dependent lysophosphatidylcholine symporter 1-B	polymer	508	56684.0	1	UniProt (Q6DEJ6) Pfam (PF13347) In PDB	Danio rerio (zebrafish)	NLS1-B,Sodium-dependent LPC symporter 1-B,Major facilitator superfamily domain-containing protein 2A-B
2	B	FAB light chain	polymer	201	20674.9	1		Mus musculus
3	C	FAB heavy chain	polymer	203	20568.0	1		Mus musculus
4	A, B	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	10	Chemie (LMT)
5		water	water		18.0	4	Chemie (HOH)

Sequence modifications

A: 22 - 509 (UniProt: Q6DEJ6)

PDB	External Database	Details
Met 2	-	initiating methionine
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Glu 13	-	expression tag
Asn 14	-	expression tag
Leu 15	-	expression tag
Tyr 16	-	expression tag
Phe 17	-	expression tag
Gln 18	-	expression tag
Gly 19	-	expression tag
Gly 20	-	expression tag
Ser 21	-	expression tag
Gln 214	Asn 214	engineered mutation
Gln 225	Asn 225	engineered mutation
Gln 509	Asn 509	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	97926.9
Non-Polymers*	Number of molecules	10
	Total formula weight	5106.1
All*	Total formula weight	103033.1

*Water molecules are not included.