8D24
Crystal structure of Plasmodium falciparum GRP78-NBD in complex with VER155008
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Chaperone DnaK | polymer | 397 | 44360.4 | 1 | UniProt (W4J0F1) Pfam (PF00012) | Plasmodium falciparum | |
| 2 | B (A) | 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile | non-polymer | 556.4 | 1 | Chemie (3FD) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence modifications
A: 26 - 404 (UniProt: W4J0F1)
| PDB | External Database | Details |
|---|---|---|
| Met 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| Ser 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Arg 18 | - | expression tag |
| Glu 19 | - | expression tag |
| Asn 20 | - | expression tag |
| Leu 21 | - | expression tag |
| Tyr 22 | - | expression tag |
| Phe 23 | - | expression tag |
| Gln 24 | - | expression tag |
| Gly 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44360.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 748.5 | |
| All* | Total formula weight | 45108.9 |
