8D1S

Crystal structure of Plasmodium falciparum GRP78 in complex with Toyocamycin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Chaperone DnaK	polymer	397	44360.4	1	UniProt (W4J0F1) Pfam (PF00012)	Plasmodium falciparum
2	B (A)	4-amino-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile	non-polymer		291.3	1	Chemie (TO1)
3	C, D (A)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	E (A)	water	water		18.0	237	Chemie (HOH)

Sequence modifications

A: 26 - 404 (UniProt: W4J0F1)

PDB	External Database	Details
Met 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
Ser 15	-	expression tag
Ser 16	-	expression tag
Gly 17	-	expression tag
Arg 18	-	expression tag
Glu 19	-	expression tag
Asn 20	-	expression tag
Leu 21	-	expression tag
Tyr 22	-	expression tag
Phe 23	-	expression tag
Gln 24	-	expression tag
Gly 25	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44360.4
Non-Polymers*	Number of molecules	3
	Total formula weight	483.4
All*	Total formula weight	44843.8

*Water molecules are not included.