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8D0F

Human SARM1 TIR domain bound to NB-2-ADPR

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BNAD(+) hydrolase SARM1polymer14316205.62UniProt (Q6SZW1)
Pfam (PF13676)
In PDB
Homo sapiens (human)NADase SARM1,hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,MyD88-5,SAM domain-containing protein 2,Tir-1 homolog,HsTIR
2A, B[[(3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-[4-[[methyl-[2,2,2-tris(fluoranyl)ethylcarbamoyl]amino]methyl]pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphatenon-polymer789.52Chemie (Q0U)
3waterwater18.0166Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight32411.1
Non-Polymers*Number of molecules2
Total formula weight1579.0
All*Total formula weight33990.2
*Water molecules are not included.

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PDB entries from 2024-07-10

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