8D0C
Human SARM1 TIR domain bound to NB-3-ADPR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | NAD(+) hydrolase SARM1 | polymer | 143 | 16205.6 | 2 | UniProt (Q6SZW1) Pfam (PF13676) In PDB | Homo sapiens (human) | NADase SARM1,hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,MyD88-5,SAM domain-containing protein 2,Tir-1 homolog,HsTIR |
2 | A, B | [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-[4-[(1~{S})-1-[methyl-[2,2,2-tris(fluoranyl)ethylcarbamoyl]amino]ethyl]pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | non-polymer | 803.6 | 2 | Chemie (Q1F) | |||
3 | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 32411.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1607.1 | |
All* | Total formula weight | 34018.3 |