8CYZ
Crystal structure of SARS-CoV-2 Mpro with compound C4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3C-like proteinase | polymer | 306 | 33825.5 | 4 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | E, F, G, H (A, B, C, D) | N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-[4-(methylsulfanyl)phenyl]acetamide | non-polymer | 439.0 | 4 | Chemie (P6I) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 612 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 135302.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1756.0 | |
| All* | Total formula weight | 137058.2 |
