8CWK

Fab arm of antibodies 4G1-C2 and 10G4 bound to CoV-2 receptor binding domain (RBD)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	Heavy chain of Fab arm of antibody 10G4	polymer	228	24475.3	1		Homo sapiens (human)
2	L	Light chain of Fab arm of antibody 10G4	polymer	215	23591.2	1		Homo sapiens (Human)
3	A	Heavy chain of Fab arm of antibody 4G1-C2	polymer	232	24809.6	1		Homo sapiens (Human)
4	B	Light chain of Fab arm of antibody 4G1-C2	polymer	215	23614.2	1	UniProt (Q6GMX0) Pfam (PF07686) Pfam (PF07654) In PDB	Homo sapiens (human)
5	C	Spike protein S1	polymer	204	22975.7	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
6	H, L, A, B, C	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
7	L, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
8		water	water		18.0	177	Chemie (HOH)

Sequence modifications

B: 1 - 214 (UniProt: Q6GMX0)

PDB	External Database	Details
Tyr 28	Asn 50	conflict
Tyr 30	Asn 52	conflict
Asp 31	Asn 53	conflict
Asp 32	Tyr 54	conflict
Gln 38	Leu 60	conflict
Lys 45	Asn 67	conflict
Ser 50	Ala 72	conflict
Gln 79	Arg 101	conflict
Glu 81	Asp 103	conflict
Ala 91	Ser 113	conflict
Trp 92	Tyr 114	conflict
Pro 93	Asn 115	conflict
Tyr 94	Ile 116	conflict
Gln 100	Gly 122	conflict
Lys 103	Asn 125	conflict
Ser 215	-	expression tag

C: 333 - 528 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 529	-	expression tag
Ser 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	119465.9
Non-Polymers*	Number of molecules	8
	Total formula weight	995.0
All*	Total formula weight	120460.9

*Water molecules are not included.