8CWI

Fab arm of antibody 10G4 bound to CoV-2 receptor binding domain (RBD)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Spike protein S1	polymer	204	22975.7	1	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2
2	B (H)	Heavy chain of Fab arm of antibody 10G4	polymer	228	24475.3	1		Homo sapiens (Human)
3	C (L)	Light chain of Fab arm of antibody 10G4	polymer	215	23591.2	1		Homo sapiens (Human)
4	D (B)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1057.0	1	In PDB GlyTouCan (G82348BZ)
5	E (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
6	F, I (A, L)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
7	G, H, J (H, L)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
8	K, L, M (A, H, L)	water	water		18.0	667	Chemie (HOH)

Sequence modifications

A: 333 - 528 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 529	-	expression tag
Ser 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	71042.2
Branched	Number of molecules	2
	Total formula weight	1627.5
Non-Polymers*	Number of molecules	5
	Total formula weight	155.0
All*	Total formula weight	72824.7

*Water molecules are not included.