8CVQ
Crystal structure of TDP1 complexed with compound XZ761
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosyl-DNA phosphodiesterase 1 | polymer | 461 | 52126.3 | 2 | UniProt (Q9NUW8) Pfam (PF06087) | Homo sapiens (human) | Tyr-DNA phosphodiesterase 1 |
| 2 | C, H (A, B) | 4-{[(4S)-2,7-diphenylimidazo[1,2-a]pyridin-3-yl]amino}benzene-1,2-dicarboxylic acid | non-polymer | 449.5 | 2 | Chemie (OYH) | |||
| 3 | D, I (A, B) | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | non-polymer | 209.3 | 2 | Chemie (MPO) | |||
| 4 | E, F, G, J, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 793 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104252.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1751.9 | |
| All* | Total formula weight | 106004.6 |
