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8CVE

Structure of L289F Hyoscyamine 6-beta Hydroxylase in complex with iron, 2-oxoglutarate, and hyoscyamine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHyoscyamine 6-beta-hydroxylasepolymer38542667.01UniProt (Q9XJ43)
Pfam (PF14226)
Pfam (PF03171)
In PDB
Atropa belladonna (belladonna)
2AFE (II) IONnon-polymer55.81Chemie (FE2)
3A1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4AFORMIC ACIDnon-polymer46.07Chemie (FMT)
5A[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoatenon-polymer289.41Chemie (HYO)
6A2-OXOGLUTARIC ACIDnon-polymer146.11Chemie (AKG)
7ASTRONTIUM IONnon-polymer87.62Chemie (SR)
8waterwater18.0311Chemie (HOH)
Sequence modifications
A: 1 - 343 (UniProt: Q9XJ43)
PDBExternal DatabaseDetails
Phe 289Leu 289engineered mutation
Gly 344-expression tag
Gly 345-expression tag
Lys 346-expression tag
Gly 347-expression tag
Pro 348-expression tag
Gly 349-expression tag
Asp 350-expression tag
Gly 351-expression tag
Pro 352-expression tag
Gly 353-expression tag
Gly 354-expression tag
Ser 355-expression tag
Gly 356-expression tag
Gly 357-expression tag
Pro 358-expression tag
Arg 359-expression tag
Gly 360-expression tag
Gly 361-expression tag
Glu 362-expression tag
Asn 363-expression tag
Leu 364-expression tag
Tyr 365-expression tag
Phe 366-expression tag
Gln 367-expression tag
Ser 368-expression tag
Gly 369-expression tag
His 370-expression tag
His 371-expression tag
His 372-expression tag
His 373-expression tag
His 374-expression tag
His 375-expression tag
His 376-expression tag
His 377-expression tag
Gly 378-expression tag
Gly 379-expression tag
Arg 380-expression tag
Gly 381-expression tag
Gly 382-expression tag
Ala 383-expression tag
Ala 384-expression tag
Ala 385-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42667.0
Non-Polymers*Number of molecules15
Total formula weight1174.9
All*Total formula weight43841.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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