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8CTF

The N-terminal domain of PA endonuclease from the influenza H1N1 viral polymerase in complex with 3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Polymerase acidic proteinpolymer19222484.71UniProt (C3W5S0)Influenza A virusRNA-directed RNA polymerase subunit P2
2B
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
3C
(A)
3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acidnon-polymer155.11Chemie (Q3O)
4D, E
(A)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
5F
(A)
waterwater18.053Chemie (HOH)
Sequence modifications
A: 1 - 198 (UniProt: C3W5S0)
PDBExternal DatabaseDetails
Met -5-initiating methionine
Gly -4-expression tag
Ser -3-expression tag
Gly -2-expression tag
Met -1-expression tag
Ser 0-expression tag
Gly 52His 52conflict
-Phe 53deletion
-Ile 54deletion
-Asp 55deletion
-Glu 56deletion
-Arg 57deletion
-Gly 58deletion
-Glu 59deletion
-Ser 60deletion
-Ile 61deletion
-Ile 62deletion
-Val 63deletion
-Glu 64deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight22484.7
Non-Polymers*Number of molecules4
Total formula weight324.0
All*Total formula weight22808.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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