8CRM
Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 11C6 refined against anomalous diffraction data
Replaces: 8AZ9Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Host translation inhibitor nsp1 | polymer | 118 | 13109.2 | 1 | UniProt (P0DTD1) Pfam (PF11501) UniProt (by SIFTS) (P0DTC1) | Severe acute respiratory syndrome coronavirus 2 | Leader protein,Non-structural protein 1,nsp1 |
| 2 | B (A) | 1-[2-(3-chlorophenyl)-1,3-thiazol-4-yl]-~{N}-methyl-methanamine | non-polymer | 238.7 | 1 | Chemie (OF6) | |||
| 3 | C (A) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A: 10 - 126 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Met 9 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13109.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 238.7 | |
| All* | Total formula weight | 13347.9 |
