8CRK

Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 7H2 refined against anomalous diffraction data

Replaces:  8AYW

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Host translation inhibitor nsp1	polymer	118	13109.2	1	UniProt (P0DTD1) Pfam (PF11501)	Severe acute respiratory syndrome coronavirus 2	Leader protein,Non-structural protein 1,nsp1
2	B (B)	(1~{R})-1-(4-chlorophenyl)ethanamine	non-polymer		155.6	1	Chemie (OG3)
3	C (B)	water	water		18.0	112	Chemie (HOH)

Sequence modifications

B: 10 - 126 (UniProt: P0DTD1)

PDB	External Database	Details
Met 9	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	13109.2
Non-Polymers*	Number of molecules	1
	Total formula weight	155.6
All*	Total formula weight	13264.8

*Water molecules are not included.