8COT
Complex of human soluble adenylyl cyclase 10 catalytic core with inhibitor TDI-10962
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Adenylate cyclase type 10 | polymer | 475 | 54269.7 | 1 | UniProt (Q96PN6) Pfam (PF00211) In PDB | Homo sapiens (human) | AH-related protein,Adenylate cyclase homolog,Germ cell soluble adenylyl cyclase,sAC,Testicular soluble adenylyl cyclase |
2 | A | 2-(dimethylamino)ethyl 5-(2-azanyl-6-chloranyl-pyrimidin-4-yl)-2-methyl-4-(phenylmethyl)pyrazole-3-carboxylate | non-polymer | 414.9 | 1 | Chemie (VBB) | |||
3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
5 | A | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
6 | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 1 - 469 (UniProt: Q96PN6)
PDB | External Database | Details |
---|---|---|
His 470 | - | expression tag |
His 471 | - | expression tag |
His 472 | - | expression tag |
His 473 | - | expression tag |
His 474 | - | expression tag |
His 475 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 54269.7 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1270.9 | |
All* | Total formula weight | 55540.6 |