8CO3
Three dimensional structure of human carbonic anhydrase XII in complex with sulfonamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Carbonic anhydrase 12 | polymer | 263 | 29857.2 | 4 | UniProt (O43570) Pfam (PF00194) In PDB | Homo sapiens (human) | Carbonate dehydratase XII,Carbonic anhydrase XII,CA-XII,Tumor antigen HOM-RCC-3.1.3 |
2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | A, B, C, D | 5-(5-methyl-6-quinolin-5-yl-pyridin-3-yl)thiophene-2-sulfonamide | non-polymer | 381.5 | 4 | Chemie (V8O) | |||
4 | water | water | 18.0 | 1202 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 3 - 269 (UniProt: O43570)
PDB | External Database | Details |
---|---|---|
Ala 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 119428.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1787.5 | |
All* | Total formula weight | 121216.3 |