8CO3
Three dimensional structure of human carbonic anhydrase XII in complex with sulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Carbonic anhydrase 12 | polymer | 263 | 29857.2 | 4 | UniProt (O43570) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase XII,Carbonic anhydrase XII,CA-XII,Tumor antigen HOM-RCC-3.1.3 |
| 2 | E, G, I, K (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, H, J, L (A, B, C, D) | 5-(5-methyl-6-quinolin-5-yl-pyridin-3-yl)thiophene-2-sulfonamide | non-polymer | 381.5 | 4 | Chemie (V8O) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 1202 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 3 - 269 (UniProt: O43570)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 119428.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1787.5 | |
| All* | Total formula weight | 121216.3 |
