8CNB
Crystal structure of CREBBP-Y1503C histone acetyltransferase domain in complex with Coenzyme A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | histone acetyltransferase | polymer | 619 | 72450.6 | 1 | UniProt (F8VPR5) Pfam (PF00439) Pfam (PF06001) Pfam (PF08214) Pfam (PF00569) UniProt (by SIFTS) (P45481) | Mus musculus (house mouse) | |
| 2 | B, C, D, E (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F (A) | COENZYME A | non-polymer | 767.5 | 1 | Chemie (COA) | |||
| 4 | G (A) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 1078 - 1554 (UniProt: F8VPR5)
A: 1619 - 1750 (UniProt: F8VPR5)
| PDB | External Database | Details |
|---|---|---|
| Met 1075 | - | initiating methionine |
| Gly 1076 | - | expression tag |
| Ser 1077 | - | expression tag |
| Cys 1503 | Tyr 1504 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Glu 1555 | - | linker |
| Ser 1613 | - | linker |
| Gly 1614 | - | linker |
| Gly 1615 | - | linker |
| Ser 1616 | - | linker |
| Gly 1617 | - | linker |
| Ser 1618 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 72450.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1029.2 | |
| All* | Total formula weight | 73479.8 |
