8CMW
A225L variant of the CODH/ACS complex of C. hydrogenoformans
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Carbon monoxide dehydrogenase | polymer | 669 | 73172.1 | 1 | Carboxydothermus hydrogenoformans Z-2901 | ||
| 2 | B | CO-methylating acetyl-CoA synthase | polymer | 730 | 82153.3 | 1 | UniProt (Q3ACS4) Pfam (PF18537) Pfam (PF03598) Pfam (PF19436) In PDB | Carboxydothermus hydrogenoformans Z-2901 | |
| 3 | D | S-HYDROXYCYSTEINE | polymer | 2 | 123.2 | 1 | synthetic construct | ||
| 4 | A | Fe(3)-Ni(1)-S(4) cluster | non-polymer | 410.3 | 1 | Chemie (RQM) | |||
| 5 | A | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 1 | Chemie (FES) | |||
| 6 | A, B | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 2 | Chemie (SF4) | |||
| 7 | A | HYDROXIDE ION | non-polymer | 17.0 | 1 | Chemie (OH) | |||
| 8 | B | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 9 | B | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 10 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 11 | B | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 12 | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A: 2 - 545 (PDB: 8CMW)
A: 546 - 670 (PDB: 8CMW)
B: 5 - 732 (UniProt: Q3ACS4)
A: 546 - 670 (PDB: 8CMW)
B: 5 - 732 (UniProt: Q3ACS4)
| PDB | External Database | Details |
|---|---|---|
| Leu 225 | Ala 225 | engineered mutation |
| Arg 733 | - | expression tag |
| Ser 734 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 155448.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1624.0 | |
| All* | Total formula weight | 157072.6 |
