8CLE
Vinblastine bound to tubulin (T2R-TTL) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Tubulin alpha-1B chain | polymer | 440 | 48966.3 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (cattle) | |
| 2 | C, F (D, B) | Tubulin beta-2B chain | polymer | 431 | 48391.4 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (cattle) | |
| 3 | D (E) | Stathmin-4 | polymer | 120 | 14207.3 | 1 | Pfam (PF00836) UniProt (by SIFTS) (P63043) | synthetic construct | |
| 4 | E (F) | Tubulin-Tyrosine Ligase | polymer | 331 | 38500.0 | 1 | Pfam (PF03133) UniProt (by SIFTS) (A0A8V0Z8P0) | synthetic construct | |
| 5 | G, K (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 6 | H, L (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 7 | I, M (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 8 | J (C) | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE | non-polymer | 811.0 | 1 | Chemie (VLB) | |||
| 9 | N, O (D, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 10 | P, Q, R, S, T... (A, C, D, E, F...) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 247422.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2872.5 | |
| All* | Total formula weight | 250295.3 |
