8CLE
Vinblastine bound to tubulin (T2R-TTL) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Tubulin alpha-1B chain | polymer | 440 | 48966.3 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (cattle) | |
| 2 | C, F (D, B) | Tubulin beta-2B chain | polymer | 431 | 48391.4 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (cattle) | |
| 3 | D (E) | Stathmin-4 | polymer | 120 | 14207.3 | 1 | Pfam (PF00836) UniProt (by SIFTS) (P63043) | synthetic construct | |
| 4 | E (F) | Tubulin-Tyrosine Ligase | polymer | 331 | 38500.0 | 1 | Pfam (PF03133) UniProt (by SIFTS) (A0A8V0Z8P0) | synthetic construct | |
| 5 | G, K (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 6 | H, L (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | I, M (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 8 | J (C) | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE | non-polymer | 811.0 | 1 | Chemie (VLB) | |||
| 9 | N, O (D, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 10 | P, Q, R, S, T... (A, C, D, E, F...) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 247422.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2872.5 | |
| All* | Total formula weight | 250295.3 |
