8CI3

Structure of bovine CD46 ectodomain (SCR 1-2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Membrane cofactor protein	polymer	136	14965.7	2	UniProt (Q6VE48) Pfam (PF00084) In PDB	Bos taurus (cattle)
2	C, D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
3	E	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
4	A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6		water	water		18.0	62	Chemie (HOH)

Sequence modifications

A, B: 40 - 175 (UniProt: Q6VE48)

PDB	External Database	Details
Glu 40	Ser 40	conflict
Thr 41	Asp 41	conflict
Gly 42	Ala 42	conflict
Arg 73	His 73	conflict
Ala 126	Glu 126	conflict
His 170	Leu 170	conflict
His 171	Cys 171	conflict
His 172	Gln 172	conflict
His 173	Pro 173	conflict
His 174	Pro 174	conflict
His 175	Pro 175	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29931.3
Branched	Number of molecules	3
	Total formula weight	1435.3
Non-Polymers*	Number of molecules	3
	Total formula weight	292.1
All*	Total formula weight	31658.8

*Water molecules are not included.