8CG1
Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment H12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, G...) | Adenosylhomocysteinase | polymer | 472 | 51735.0 | 8 | UniProt (Q9I685) Pfam (PF05221) Pfam (PF00670) | Pseudomonas aeruginosa PAO1 | S-adenosyl-L-homocysteine hydrolase,AdoHcyase |
| 2 | CA, GB, I, JA, P... (D, J, A, G, B...) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) | |||
| 3 | DA, HB, J, KA, Q... (D, J, A, G, B...) | ADENINE | non-polymer | 135.1 | 8 | Chemie (ADE) | |||
| 4 | BB, FA, IB, K, LA... (I, D, J, A, G...) | POTASSIUM ION | non-polymer | 39.1 | 8 | Chemie (K) | |||
| 5 | AA, BA, CB, DB, EB... (C, I, D, J, A...) | PHOSPHATE ION | non-polymer | 95.0 | 26 | Chemie (PO4) | |||
| 6 | AB, EA, R, TA, X (I, D, B, H, C) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 5 | Chemie (DMS) | |||
| 7 | SA (H) | ~{N}-(2-thiophen-2-ylethyl)pyridine-4-carboxamide | non-polymer | 232.3 | 1 | Chemie (SZA) | |||
| 8 | MB, NB, OB, PB, QB... (A, B, C, D, G...) | water | water | 18.0 | 2509 | Chemie (HOH) |
Sequence modifications
A, B, C, D, G, H, I, J: 1 - 469 (UniProt: Q9I685)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 413880.2 | |
| Non-Polymers* | Number of molecules | 56 |
| Total formula weight | 9793.4 | |
| All* | Total formula weight | 423673.7 |
