8CFT
Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment G12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Adenosylhomocysteinase | polymer | 472 | 51735.0 | 4 | UniProt (Q9I685) Pfam (PF05221) Pfam (PF00670) | Pseudomonas aeruginosa PAO1 | S-adenosyl-L-homocysteine hydrolase,AdoHcyase |
| 2 | BA, E, M, R (D, A, B, C) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | CA, F, N, S (D, A, B, C) | ADENINE | non-polymer | 135.1 | 4 | Chemie (ADE) | |||
| 4 | AA, EA, G (C, D, A) | ~{N}-[(~{E})-thiophen-2-ylmethylideneamino]cyclopropanecarboxamide | non-polymer | 194.3 | 3 | Chemie (SZ7) | |||
| 5 | GA, H, O, U (D, A, B, C) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 6 | HA, I, IA, J, JA... (D, A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 15 | Chemie (PO4) | |||
| 7 | DA, FA, T (D, C) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 8 | LA, MA, NA, OA (A, B, C, D) | water | water | 18.0 | 1801 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 469 (UniProt: Q9I685)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 206940.1 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 5592.3 | |
| All* | Total formula weight | 212532.4 |
