8CEX
Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH11227.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | N-glycosylase/DNA lyase | polymer | 318 | 35816.7 | 3 | UniProt (O08760) Pfam (PF07934) Pfam (PF00730) | Mus musculus (house mouse) | |
| 2 | D (A) | 6-fluoranyl-N-[(4-methylphenyl)methyl]pyridine-3-carboxamide | non-polymer | 244.3 | 1 | Chemie (UG0) | |||
| 3 | E (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 4 | F, G, H (A, B, C) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A, B, C: 11 - 325 (UniProt: O08760)
| PDB | External Database | Details |
|---|---|---|
| Gly 8 | - | expression tag |
| Ser 9 | - | expression tag |
| His 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 107450.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 303.0 | |
| All* | Total formula weight | 107752.9 |
