Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8CEN

Yeast RNA polymerase II transcription pre-initiation complex with core Mediator

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
10General transcription and DNA repair factor IIH helicase subunit XPDpolymer77889899.01UniProt (P06839)
Pfam (PF06733)
Pfam (PF06777)
Pfam (PF13307)
In PDB		Saccharomyces cerevisiae (baker's yeast)TFIIH subunit XPD,DNA repair helicase RAD3,RNA polymerase II transcription factor B subunit RAD3,TFB subunit RAD3
21General transcription and DNA repair factor IIH subunit TFB1polymer64272993.31Saccharomyces cerevisiae
32General transcription and DNA repair factor IIH subunit TFB2polymer51358602.31Saccharomyces cerevisiae
43RNA polymerase II transcription factor B subunit 3polymer32138188.41Saccharomyces cerevisiae
54General transcription and DNA repair factor IIH subunit TFB4polymer33837506.41Saccharomyces cerevisiae
65General transcription and DNA repair factor IIH subunit TFB5polymer728243.51Saccharomyces cerevisiae
76General transcription and DNA repair factor IIH subunit SSL1polymer46152370.01Saccharomyces cerevisiae
87General transcription and DNA repair factor IIH helicase subunit XPBpolymer84395461.71UniProt (Q00578)
Pfam (PF13625)
Pfam (PF04851)
Pfam (PF16203)
In PDB		Saccharomyces cerevisiae (baker's yeast)TFIIH subunit XPB,DNA repair helicase RAD25,RNA polymerase II transcription factor B subunit SSL2,TFB subunit SSL2,Suppressor of stem-loop mutation 2
9ADNA-directed RNA polymerase II subunit RPB1polymer1733191821.61UniProt (P04050)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
Pfam (PF05001)
Pfam (PF04997)
Pfam (PF00623)
Pfam (PF04983)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerase II subunit B1,DNA-directed RNA polymerase III largest subunit,RNA polymerase II subunit B220
10BDNA-directed RNA polymerase II subunit RPB2polymer1224138937.31UniProt (P08518)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerase II subunit 2,B150,DNA-directed RNA polymerase II 140 kDa polypeptide
11CDNA-directed RNA polymerase II subunit RPB3polymer34738635.91UniProt (P16370)
Pfam (PF01193)
Pfam (PF01000)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerase II subunit 3,RNA polymerase II subunit B3,B44.5,DNA-directed RNA polymerase II 45 kDa polypeptide
12DDNA-directed RNA polymerase II subunit RPB4polymer22125451.21UniProt (P20433)
Pfam (PF03874)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerase II subunit B4,B32,DNA-directed RNA polymerase II 32 kDa polypeptide
13EDNA-directed RNA polymerases I, II, and III subunit RPABC1polymer21525117.11UniProt (P20434)
Pfam (PF03871)
Pfam (PF01191)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerases I,II,and III subunit ABC1,ABC27,DNA-directed RNA polymerases I,and III 27 kDa polypeptide
14FDNA-directed RNA polymerases I, II, and III subunit RPABC2polymer15517931.81UniProt (P20435)
Pfam (PF01192)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerases I,II,and III subunit ABC2,ABC23,DNA-directed RNA polymerases I,and III 23 kDa polypeptide
15GDNA-directed RNA polymerase II subunit RPB7polymer17719909.91UniProt (P34087)
Pfam (PF03876)
Pfam (PF00575)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerase II subunit B7,B16
16HDNA-directed RNA polymerases I, II, and III subunit RPABC3polymer14616525.41UniProt (P20436)
Pfam (PF03870)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerases I,II,and III subunit ABC3,ABC14.4,ABC14.5,DNA-directed RNA polymerases I,and III 14.5 kDa polypeptide
17IDNA-directed RNA polymerase II subunit RPB9polymer12214308.21UniProt (P27999)
Pfam (PF02150)
Pfam (PF01096)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerase II subunit B9,B12.6,DNA-directed RNA polymerase II 14.2 kDa polypeptide,DNA-directed RNA polymerase II subunit 9
18JDNA-directed RNA polymerases I, II, and III subunit RPABC5polymer708290.71UniProt (P22139)
Pfam (PF01194)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerases I,II,and III subunit ABC5,ABC10-beta,ABC8,DNA-directed RNA polymerases I,and III 8.3 kDa polypeptide
19KDNA-directed RNA polymerase II subunit RPB11polymer12013633.51UniProt (P38902)
Pfam (PF13656)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerase II subunit B11,B13.6,DNA-directed RNA polymerase II 13.6 kDa polypeptide
20LDNA-directed RNA polymerases I, II, and III subunit RPABC4polymer707730.01UniProt (P40422)
Pfam (PF03604)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerases I,II,and III subunit ABC4,ABC10-alpha
21MTranscription initiation factor IIBpolymer35239215.41UniProt (P29055)
Pfam (PF08271)
Pfam (PF00382)
In PDB		Saccharomyces cerevisiae (baker's yeast)General transcription factor TFIIB,Transcription factor E
22NNONTEMPLATE DNA (209-MER)polymer20964291.01synthetic construct
23OTATA-binding proteinpolymer24027042.31UniProt (G4XSG8)
Pfam (PF00352)
In PDB		Saccharomyces cerevisiae (baker's yeast)
24QTranscription initiation factor IIF subunit alphapolymer73582320.61Saccharomyces cerevisiae
25RTranscription initiation factor IIF subunit betapolymer40046684.51UniProt (P41896)
Pfam (PF17683)
Pfam (PF02270)
In PDB		Saccharomyces cerevisiae (baker's yeast)TFIIF medium subunit,TFIIF-beta,Transcription factor G 54 kDa subunit
26TTEMPLATE DNA (209-MER)polymer20964754.31synthetic construct
27UTranscription initiation factor IIA large subunitpolymer28632230.81Saccharomyces cerevisiae
28VTranscription initiation factor IIA subunit 2polymer12213473.11UniProt (A0A6A5PRZ0)
In PDB		Saccharomyces cerevisiae (baker's yeast)
29WTranscription initiation factor IIE subunit alphapolymer49255951.01UniProt (P36100)
Pfam (PF02002)
In PDB		Saccharomyces cerevisiae (baker's yeast)TFIIE-alpha,Factor A 66 kDa subunit,Transcription factor A large subunit
30XTranscription initiation factor IIE subunit betapolymer32837050.41UniProt (P36145)
Pfam (PF02186)
Pfam (PF18121)
Pfam (PF22254)
In PDB		Saccharomyces cerevisiae (baker's yeast)TFIIE-beta,Factor A 43 kDa subunit,Transcription factor A small subunit
31aMediator of RNA polymerase II transcription subunit 6polymer29532844.71Saccharomyces cerevisiae
32bMediator of RNA polymerase II transcription subunit 8polymer22325297.21Saccharomyces cerevisiae
33cMediator of RNA polymerase II transcription subunit 11polymer11513324.21Saccharomyces cerevisiae
34dMediator of RNA polymerase II transcription subunit 17polymer68778582.81Saccharomyces cerevisiae
35eMediator of RNA polymerase II transcription subunit 18polymer30734316.51Saccharomyces cerevisiae
36fMediator of RNA polymerase II transcription subunit 20polymer21022918.11Saccharomyces cerevisiae
37gMediator of RNA polymerase II transcription subunit 22polymer12113875.71Saccharomyces cerevisiae
38hMediator of RNA polymerase II transcription subunit 4polymer28432244.91Saccharomyces cerevisiae
39iMediator of RNA polymerase II transcription subunit 7polymer22225616.11Saccharomyces cerevisiae
40jMediator of RNA polymerase II transcription subunit 9polymer14917400.41Saccharomyces cerevisiae
41kMediator of RNA polymerase II transcription subunit 10polymer15717927.91Saccharomyces cerevisiae
42lMediator of RNA polymerase II transcription subunit 14polymer74584746.51Saccharomyces cerevisiae
43mMediator of RNA polymerase II transcription subunit 19polymer22024885.31Saccharomyces cerevisiae
44nMediator of RNA polymerase II transcription subunit 21polymer14016093.41Saccharomyces cerevisiae
45oMediator of RNA polymerase II transcription subunit 31polymer12714747.71Saccharomyces cerevisiae
46pMediator of RNA polymerase II transcription subunit 1polymer56664315.01Saccharomyces cerevisiae
470IRON/SULFUR CLUSTERnon-polymer351.61Chemie (SF4)
486, A, B, C, I...ZINC IONnon-polymer65.417Chemie (ZN)
49AMAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence modifications
C: 4 - 318 (UniProt: P16370)
PDBExternal DatabaseDetails
Met -28-initiating methionine
Gly -27-expression tag
Ser -26-expression tag
His -25-expression tag
His -24-expression tag
His -23-expression tag
His -22-expression tag
His -21-expression tag
His -20-expression tag
Ser -19-expression tag
Asn -18-expression tag
Ser -17-expression tag
Gly -16-expression tag
Leu -15-expression tag
Asn -14-expression tag
Asp -13-expression tag
Ile -12-expression tag
Phe -11-expression tag
Glu -10-expression tag
Ala -9-expression tag
Gln -8-expression tag
Lys -7-expression tag
Ile -6-expression tag
Glu -5-expression tag
Trp -4-expression tag
His -3-expression tag
Glu -2-expression tag
Asp -1-expression tag
Thr 0-expression tag
Gly 1-expression tag
Ser 2-expression tag
Ser 3-expression tag
G: 1 - 171 (UniProt: P34087)
PDBExternal DatabaseDetails
His 172-expression tag
His 173-expression tag
His 174-expression tag
His 175-expression tag
His 176-expression tag
His 177-expression tag
M: 1 - 345 (UniProt: P29055)
PDBExternal DatabaseDetails
Lys 346-expression tag
His 347-expression tag
His 348-expression tag
His 349-expression tag
His 350-expression tag
His 351-expression tag
His 352-expression tag
W: 1 - 482 (UniProt: P36100)
PDBExternal DatabaseDetails
Ala 483-expression tag
Ala 484-expression tag
Ala 485-expression tag
Leu 486-expression tag
Glu 487-expression tag
His 488-expression tag
His 489-expression tag
His 490-expression tag
His 491-expression tag
His 492-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains46
Total formula weight1953707.2
Non-Polymers*Number of molecules19
Total formula weight1487.9
All*Total formula weight1955195.1
*Water molecules are not included.

223790

PDB entries from 2024-08-14

PDB statisticsPDBj update infoContact PDBjnumon