8CBE

SARS-CoV-2 Delta-RBD complexed with BA.4/5-2 and Beta-49 Fabs

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	BA.4/5-2 heavy chain	polymer	228	24359.3	1		Homo sapiens
2	L	BA.4/5-2 light chain	polymer	214	23388.0	1		Homo sapiens
3	E	Spike protein S1	polymer	202	22935.7	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
4	B	Beta-49 light chain	polymer	216	23566.1	1		Homo sapiens
5	A	Beta-49 heavy chain	polymer	223	23431.4	1		Homo sapiens
6	C	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)

Sequence modifications

E: 333 - 526 (UniProt: P0DTC2)

PDB	External Database	Details
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
Arg 452	Leu 452	variant
Lys 478	Thr 478	variant
Lys 527	-	expression tag
Lys 528	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	117680.6
Branched	Number of molecules	1
	Total formula weight	732.7
All*	Total formula weight	118413.3

*Water molecules are not included.