8C8T
cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with bNAbs EPTC112 and 3BNC117
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, F, G | Envelope glycoprotein gp160 | polymer | 469 | 52551.5 | 3 | UniProt (Q2N0S5) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | Env polyprotein |
2 | B, I, J | Gp41 Bg505 T332n Sosip.664 | polymer | 145 | 16431.6 | 3 | Human immunodeficiency virus 1 | ||
3 | C, H | IgG EPTC112 Fab fragment heavy chain | polymer | 233 | 25320.4 | 2 | Homo sapiens (Human) | ||
4 | R, S | IgG 3BNC117 Fab heavy chain | polymer | 226 | 24640.5 | 2 | Homo sapiens (Human) | ||
5 | T, U | IgG 3BNC117 Fab Light Chain | polymer | 206 | 23022.7 | 2 | Homo sapiens (Human) | ||
6 | D, K | IgG EPTC112 Fab Light Chain | polymer | 216 | 22680.9 | 2 | Homo sapiens (Human) | ||
7 | a, b, E, M, N... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 11 | In PDB GlyTouCan (G42666HT) | |||
8 | L, X | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
9 | V | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
10 | A, F, G, T | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 24 | Chemie (NAG) |
Sequence modifications
A, F, G: 34 - 504 (UniProt: Q2N0S5)
PDB | External Database | Details |
---|---|---|
Asn 332 | Thr 330 | conflict |
Cys 501 | Ala 498 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 14 |
Total formula weight | 398278.3 | |
Branched | Number of molecules | 14 |
Total formula weight | 6590.2 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 5309.0 | |
All* | Total formula weight | 410177.5 |