8C8C
Crystal Structure of Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PI5P4Ka) bound to an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | polymer | 375 | 42859.4 | 1 | UniProt (P48426) Pfam (PF01504) In PDB | Homo sapiens (human) | 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha,Diphosphoinositide kinase 2-alpha,PIP5KIII,Phosphatidylinositol 5-Phosphate 4-Kinase,PI5P4Kalpha,Phosphatidylinositol 5-phosphate 4-kinase type II alpha,PI(5)P 4-kinase type II alpha,PIP4KII-alpha,PtdIns(4)P-5-kinase B isoform,PtdIns(4)P-5-kinase C isoform,PtdIns(5)P-4-kinase isoform 2-alpha |
| 2 | A | ~{N}-(3-chloranyl-4-methoxy-phenyl)-7-(3,4-dimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine | non-polymer | 378.9 | 1 | Chemie (U1U) | |||
| 3 | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A: 33 - 406 (UniProt: P48426)
| PDB | External Database | Details |
|---|---|---|
| Gly 32 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42859.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 378.9 | |
| All* | Total formula weight | 43238.2 |
