8C6D
Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Genome polyprotein | polymer | 297 | 32705.8 | 1 | UniProt (A0A2L1GIK5) UniProt (by SIFTS) (Q66479) | Enterovirus A71 | |
| 2 | B (B) | Genome polyprotein (Fragment) | polymer | 323 | 35253.3 | 1 | UniProt (D4QGA2) UniProt (by SIFTS) (Q66479) | Enterovirus A71 | |
| 3 | C (C) | Genome polyprotein | polymer | 242 | 26558.4 | 1 | UniProt (D4QGA4) UniProt (by SIFTS) (Q66479) | Enterovirus A71 | |
| 4 | D (A) | (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol | non-polymer | 299.5 | 1 | Chemie (SQS) PubChem (1104) PubChem (31270) PubChem (444299) PubChem (447699) PubChem (5326412) PubChem (5353955) PubChem (5496506) PubChem (6604741) PubChem (10086129) PubChem (11130338) PubChem (12359052) PubChem (12359053) PubChem (12359056) PubChem (5280335) PubChem (54453873) PubChem (56610175) PubChem (57351389) PubChem (123484476) |
Sequence modifications
A: 1 - 297 (UniProt: A0A2L1GIK5)
C: 1 - 242 (UniProt: D4QGA4)
| PDB | External Database | Details |
|---|---|---|
| Cys 116 | Tyr 681 | conflict |
| Ile 162 | Lys 727 | conflict |
| Ala 246 | Pro 811 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 235 | Ile 558 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 94517.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 299.5 | |
| All* | Total formula weight | 94816.9 |
