8C6D
Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Genome polyprotein | polymer | 297 | 32705.8 | 1 | UniProt (A0A2L1GIK5) | Enterovirus A71 | |
| 2 | B (B) | Genome polyprotein (Fragment) | polymer | 323 | 35253.3 | 1 | UniProt (D4QGA2) | Enterovirus A71 | |
| 3 | C (C) | Genome polyprotein | polymer | 242 | 26558.4 | 1 | UniProt (D4QGA4) | Enterovirus A71 | |
| 4 | D (A) | (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol | non-polymer | 299.5 | 1 | Chemie (SQS) |
Sequence modifications
A: 1 - 297 (UniProt: A0A2L1GIK5)
C: 1 - 242 (UniProt: D4QGA4)
| PDB | External Database | Details |
|---|---|---|
| Cys 116 | Tyr 681 | conflict |
| Ile 162 | Lys 727 | conflict |
| Ala 246 | Pro 811 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 235 | Ile 558 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 94517.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 299.5 | |
| All* | Total formula weight | 94816.9 |
