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8C60

Cryo-EM structure of the human SIN3B full-length complex at 3.4 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform 2 of Paired amphipathic helix protein Sin3bpolymer1130129547.11UniProt (O75182)
Pfam (PF02671)
Pfam (PF08295)
Pfam (PF16879)
Homo sapiens (human)Histone deacetylase complex subunit Sin3b,Transcriptional corepressor Sin3b
2B
(B)
Histone deacetylase 2polymer48855443.21UniProt (Q92769)
Pfam (PF00850)
Homo sapiens (human)HD2,Protein deacylase HDAC2
3C
(C)
PHD finger protein 12polymer1004109841.61UniProt (Q96QT6)
Pfam (PF00628)
Pfam (PF16737)
Homo sapiens (human)PHD factor 1,Pf1
4D
(D)
Mortality factor 4-like protein 1polymer36241540.51UniProt (Q9UBU8)
Pfam (PF11717)
Pfam (PF22732)
Pfam (PF05712)
Homo sapiens (human)MORF-related gene 15 protein,Protein MSL3-1,Transcription factor-like protein MRG15
5E, H, I, J, K
(B, C)
ZINC IONnon-polymer65.45Chemie (ZN)
6F, G
(B)
CALCIUM IONnon-polymer40.12Chemie (CA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight336372.4
Non-Polymers*Number of molecules7
Total formula weight407.2
All*Total formula weight336779.6
*Water molecules are not included.

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PDB entries from 2025-06-25

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