8C5O

Crystal Structure of Penicillin-binding Protein 3 (PBP3) from Staphylococcus Epidermidis in complex with Vaborbactam

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Penicillin-binding protein 3	polymer	668	74932.0	1	UniProt (Q5HNZ7) Pfam (PF03717) Pfam (PF00905)	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
2	B (A)	Vaborbactam	non-polymer		297.1	1	Chemie (4D6)
3	C (A)	water	water		18.0	338	Chemie (HOH)

Sequence modifications

A: 48 - 696 (UniProt: Q5HNZ7)

PDB	External Database	Details
Gly 29	-	expression tag
Ser 30	-	expression tag
Ser 31	-	expression tag
His 32	-	expression tag
His 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
His 37	-	expression tag
Ser 38	-	expression tag
Ser 39	-	expression tag
Gly 40	-	expression tag
Glu 41	-	expression tag
Asn 42	-	expression tag
Leu 43	-	expression tag
Tyr 44	-	expression tag
Phe 45	-	expression tag
Gln 46	-	expression tag
Ser 47	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	74932.0
Non-Polymers*	Number of molecules	1
	Total formula weight	297.1
All*	Total formula weight	75229.1

*Water molecules are not included.