8C5M
SARS-CoV-2 nsp10-16 methyltransferase in complex with MTA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | 2'-O-methyltransferase nsp16 | polymer | 304 | 34150.1 | 1 | UniProt (P0DTD1) Pfam (PF06460) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 16,nsp16 |
2 | B (B) | Non-structural protein 10 | polymer | 140 | 14860.0 | 1 | UniProt (P0DTD1) Pfam (PF09401) | Severe acute respiratory syndrome coronavirus 2 | nsp10,Growth factor-like peptide,GFL |
3 | AA, BA, C, CA, D... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 33 | Chemie (EDO) | |||
4 | E (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
5 | R (A) | 5'-DEOXY-5'-METHYLTHIOADENOSINE | non-polymer | 297.3 | 1 | Chemie (MTA) | |||
6 | GA, HA (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
7 | NA, OA (A, B) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 6799 - 7096 (UniProt: P0DTD1)
B: 4254 - 4392 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Glu 7097 | - | expression tag |
Asn 7098 | - | expression tag |
Leu 7099 | - | expression tag |
Tyr 7100 | - | expression tag |
Phe 7101 | - | expression tag |
Gln 7102 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 4253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 49010.1 | |
Non-Polymers* | Number of molecules | 37 |
Total formula weight | 2671.6 | |
All* | Total formula weight | 51681.7 |