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8C5M

SARS-CoV-2 nsp10-16 methyltransferase in complex with MTA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
2'-O-methyltransferase nsp16polymer30434150.11UniProt (P0DTD1)
Pfam (PF06460)
Severe acute respiratory syndrome coronavirus 2Non-structural protein 16,nsp16
2B
(B)
Non-structural protein 10polymer14014860.01UniProt (P0DTD1)
Pfam (PF09401)
Severe acute respiratory syndrome coronavirus 2nsp10,Growth factor-like peptide,GFL
3AA, BA, C, CA, D...
(A, B)
1,2-ETHANEDIOLnon-polymer62.133Chemie (EDO)
4E
(A)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.21Chemie (MES)
5R
(A)
5'-DEOXY-5'-METHYLTHIOADENOSINEnon-polymer297.31Chemie (MTA)
6GA, HA
(B)
ZINC IONnon-polymer65.42Chemie (ZN)
7NA, OA
(A, B)
waterwater18.0272Chemie (HOH)
Sequence modifications
A: 6799 - 7096 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Glu 7097-expression tag
Asn 7098-expression tag
Leu 7099-expression tag
Tyr 7100-expression tag
Phe 7101-expression tag
Gln 7102-expression tag
B: 4254 - 4392 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Gly 4253-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight49010.1
Non-Polymers*Number of molecules37
Total formula weight2671.6
All*Total formula weight51681.7
*Water molecules are not included.

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PDB entries from 2025-01-29

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