8C5E
E. coli NfsB-T41Q/N71S/F124T mutant bound to nicotinic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Oxygen-insensitive NAD(P)H nitroreductase | polymer | 216 | 23759.9 | 2 | UniProt (P38489) Pfam (PF00881) | Escherichia coli | Dihydropteridine reductase,FMN-dependent nitroreductase |
| 2 | C, E (A, B) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 2 | Chemie (FMN) | |||
| 3 | D, F (A, B) | NICOTINIC ACID | non-polymer | 123.1 | 2 | Chemie (NIO) | |||
| 4 | G (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 511 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 217 (UniProt: P38489)
| PDB | External Database | Details |
|---|---|---|
| Gln 41 | Thr 41 | engineered mutation |
| Ser 71 | Asn 71 | engineered mutation |
| Thr 124 | Phe 124 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47519.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1221.0 | |
| All* | Total formula weight | 48740.8 |
