8C53
Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; CrystFEL processing
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Inosine-5'-monophosphate dehydrogenase | polymer | 512 | 55765.7 | 2 | UniProt (P50098) Pfam (PF00478) Pfam (PF00571) | Trypanosoma brucei | IMP dehydrogenase,IMPD,IMPDH |
| 2 | C, F (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 3 | D, G (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 4 | E, H (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 512 (UniProt: P50098)
| PDB | External Database | Details |
|---|---|---|
| Ser 488 | Thr 488 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 111531.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2090.7 | |
| All* | Total formula weight | 113622.0 |
