8C3V
SARS-CoV-2 Delta-RBD complexed with BA.2-13 Fab and C1 nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, I, K (H, A, C) | BA.2-13 heavy chain | polymer | 231 | 24766.8 | 3 | Homo sapiens | ||
| 2 | B, J, L (L, B, D) | BA.2-13 light chain | polymer | 213 | 23149.7 | 3 | Homo sapiens | ||
| 3 | C, E, G (R, X, Y) | Spike protein S1 | polymer | 202 | 22935.7 | 3 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 4 | D, F, H (I, J, K) | Nanobody C1 | polymer | 131 | 14659.1 | 3 | Lama glama | ||
| 5 | M (E) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G42466VF) | |||
| 6 | N (F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 7 | O (G) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G00395TQ) | |||
| 8 | BA, CA, EA, FA, GA... (Y, K, A, R, I...) | GLYCEROL | non-polymer | 92.1 | 14 | Chemie (GOL) | |||
| 9 | AA, R (J, R) | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 2 | Chemie (PG0) | |||
| 10 | DA, X (Y, X) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) |
Sequence modifications
R, X, Y: 333 - 528 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| His 327 | - | expression tag |
| His 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| Arg 452 | Leu 452 | conflict |
| Lys 478 | Thr 478 | conflict |
| Lys 527 | Pro 527 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 256533.9 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2522.3 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1918.1 | |
| All* | Total formula weight | 260974.3 |
