8C3P
Crystal structure of autotaxin gamma in complex with LPA 18:1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | polymer | 888 | 102023.9 | 2 | UniProt (Q13822) Pfam (PF01033) Pfam (PF01663) Pfam (PF01223) | Homo sapiens (human) | E-NPP 2,Autotaxin,Extracellular lysophospholipase D,LysoPLD |
| 2 | C, D (C, D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 3 | E, T (A, B) | 7alpha-hydroxycholesterol | non-polymer | 402.7 | 2 | Chemie (5JK) | |||
| 4 | F, V (A, B) | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate | non-polymer | 436.5 | 2 | Chemie (NKP) | |||
| 5 | CA, DA, EA, FA, G... (B, A) | IODIDE ION | non-polymer | 126.9 | 17 | Chemie (IOD) | |||
| 6 | J, K, Y, Z (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 7 | AA, BA, L, M (B, A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 8 | U (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 9 | IA, JA (A, B) | water | water | 18.0 | 510 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 888 (UniProt: Q13822)
| PDB | External Database | Details |
|---|---|---|
| Ala 54 | Asn 54 | engineered mutation |
| Ala 411 | Asn 411 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 204047.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1173.1 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 4349.8 | |
| All* | Total formula weight | 209570.6 |
