8C1Y
Small molecule stabilizer for 14-3-3/ChREBP (Cmd 30)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
2 | B | Carbohydrate-responsive element-binding protein | polymer | 18 | 2383.8 | 1 | UniProt (C9JDF5) UniProt (by SIFTS) (Q9NP71) In PDB | Homo sapiens | |
3 | B | [2-[2-[[2,2-bis(fluoranyl)-2-phenyl-ethyl]amino]-2-oxidanylidene-ethoxy]phenyl]phosphonic acid | non-polymer | 371.3 | 1 | Chemie (U0U) | |||
4 | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 28926.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 371.3 | |
All* | Total formula weight | 29297.9 |