8C1B
Focused map for structure of IgE bound to the ectodomain of FceRIa
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (H, X) | Immunoglobulin heavy constant epsilon | polymer | 319 | 35444.7 | 2 | UniProt (P01854) Pfam (PF07654) | Homo sapiens (human) | Ig epsilon chain C region,Ig epsilon chain C region ND |
| 2 | B (R) | High affinity immunoglobulin epsilon receptor subunit alpha | polymer | 169 | 19625.8 | 1 | UniProt (P12319) Pfam (PF13927) Pfam (PF13895) | Homo sapiens (human) | Fc-epsilon RI-alpha,FcERI,IgE Fc receptor subunit alpha |
| 3 | D, F (A, C) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 4 | E (B) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 5 | G, H, I (R) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
H, X: 224 - 539 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| Ser 540 | - | expression tag |
| Val 541 | - | expression tag |
| Ala 542 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 90515.2 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2408.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 93587.0 |
