8BZX
1-deoxy-D-xylulose 5-phosphate synthase from Klebsiella pneumoniae (kpDXPS),co-crystal with thiamine monophosphate analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 1-deoxy-D-xylulose-5-phosphate synthase | polymer | 586 | 63254.1 | 2 | UniProt (A0A486V6R5) UniProt (A0A483FYN3) UniProt (by SIFTS) (A6T5F3) | Klebsiella pneumoniae | 1-deoxyxylulose-5-phosphate synthase,DXP synthase,DXPS |
| 2 | C, E (A, B) | 2-[4-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-3-methyl-5-propanoyl-thiophen-2-yl]ethyl dihydrogen phosphate | non-polymer | 399.4 | 2 | Chemie (SW6) | |||
| 3 | D, F, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 230 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 197 (UniProt: A0A486V6R5)
A, B: 205 - 586 (UniProt: A0A483FYN3)
| PDB | External Database | Details |
|---|---|---|
| Gly 198 | - | linker |
| Gly 199 | - | linker |
| Gly 200 | - | linker |
| Gly 201 | - | linker |
| Gly 202 | - | linker |
| Gly 203 | - | linker |
| Gly 204 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 126508.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 871.7 | |
| All* | Total formula weight | 127380.0 |
