8BZP
JNK3 (Mitogen-activated protein kinase 10) in Complex with Compound 23 bearing a C(sp3)F2Br moiety
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mitogen-activated protein kinase 10 | polymer | 364 | 42059.7 | 2 | UniProt (P53779) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 10,MAPK 10,MAP kinase p49 3F12,Stress-activated protein kinase 1b,SAPK1b,Stress-activated protein kinase JNK3,c-Jun N-terminal kinase 3 |
| 2 | C, P (A, B) | 2-bromanyl-2,2-bis(fluoranyl)-~{N}-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ethanamide | non-polymer | 335.1 | 2 | Chemie (SWM) | |||
| 3 | D, E, J, K, Q... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | F, I, M, O, S... (A, B) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 5 | G (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 6 | H, L (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 7 | N, W, X (A, B) | N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE | non-polymer | 336.6 | 3 | Chemie (C15) | |||
| 8 | Y (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 9 | AA, Z (B, A) | water | water | 18.0 | 287 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84119.4 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 3114.9 | |
| All* | Total formula weight | 87234.3 |
