8BYZ
fragment-linked stabilizer for ERa - 14-3-3 interaction (AZ210)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
2 | B | ERalpha peptide | polymer | 5 | 613.6 | 1 | UniProt (by SIFTS) (P03372) In PDB | Homo sapiens | |
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A | 4-[(2~{S})-3-azanyl-2-methyl-propyl]-7-methoxy-1-benzothiophene-2-carboximidamide | non-polymer | 277.4 | 1 | Chemie (SD7) | |||
5 | water | water | 18.0 | 318 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27156.5 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 326.0 | |
All* | Total formula weight | 27482.5 |