8BYK

The structure of MadC from Clostridium maddingley reveals new insights into class I lanthipeptide cyclases

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Lanthionine synthetase C-like protein	polymer	449	50820.5	1	UniProt (K6THC9) UniProt (by SIFTS) (A0ACD6B9R6)	Clostridium
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	C, D (A)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4	E, F, G (A)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	3	Chemie (MPD)
5	H (A)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
6	I (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7	J (A)	water	water		18.0	294	Chemie (HOH)

Sequence modifications

A: 1 - 438 (UniProt: K6THC9)

PDB	External Database	Details
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Ala 498	-	expression tag
Ala 499	-	expression tag
Ala 500	-	expression tag
His 501	-	expression tag
His 502	-	expression tag
Ala 503	-	expression tag
Ala 504	-	expression tag
Ala 505	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	50820.5
Non-Polymers*	Number of molecules	8
	Total formula weight	560.4
All*	Total formula weight	51380.9

*Water molecules are not included.