8BYJ
The structures of Ace2 in complex with bicyclic peptide inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Processed angiotensin-converting enzyme 2 | polymer | 609 | 70587.2 | 2 | UniProt (Q9BYF1) Pfam (PF01401) In PDB | Homo sapiens (human) | |
2 | C, D | ALA-CYS-VAL-ARG-SER-HIS-CYS-SER-SER-LEU-LEU-PRO-ARG-ILE-HIS-CYS-ALA | polymer | 18 | 1855.2 | 2 | synthetic construct | ||
3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
5 | C, D | 1-[3,5-bis(3-bromanylpropanoyl)-1,3,5-triazinan-1-yl]-3-bromanyl-propan-1-one | non-polymer | 492.0 | 2 | Chemie (LFI) | |||
6 | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A, B: 19 - 615 (UniProt: Q9BYF1)
PDB | External Database | Details |
---|---|---|
Gly 18 | - | expression tag |
Ser 616 | - | expression tag |
Ser 617 | - | expression tag |
Pro 618 | - | expression tag |
His 619 | - | expression tag |
His 620 | - | expression tag |
His 621 | - | expression tag |
His 622 | - | expression tag |
His 623 | - | expression tag |
His 624 | - | expression tag |
His 625 | - | expression tag |
His 626 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 144884.9 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1137.8 | |
All* | Total formula weight | 146022.7 |