8BWZ
fragment-linked stabilizer for ERa - 14-3-3 interaction (1074393)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 14-3-3 protein sigma | polymer | 236 | 26558.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
2 | B | ERalpha peptide | polymer | 5 | 613.6 | 1 | UniProt (by SIFTS) (P03372) In PDB | Homo sapiens | |
3 | A | ~{N}-[3-(5-carbamimidoylthiophen-3-yl)phenyl]-2-(4-ethanoylphenoxy)-2-methyl-propanamide | non-polymer | 421.5 | 1 | Chemie (S3I) | |||
4 | water | water | 18.0 | 375 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27172.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 421.5 | |
All* | Total formula weight | 27594.0 |