8BWQ
Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with topotecan)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ATP-binding cassette sub-family C member 4 | polymer | 1325 | 149693.9 | 1 | UniProt (O15439) Pfam (PF00664) Pfam (PF00005) In PDB | Homo sapiens (human) | MRP/cMOAT-related ABC transporter,Multi-specific organic anion transporter B,MOAT-B,Multidrug resistance-associated protein 4 |
2 | A | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE | non-polymer | 421.4 | 1 | Chemie (TTC) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 149693.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 421.4 | |
All* | Total formula weight | 150115.4 |