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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8BTK

Structure of the TRAP complex with the Sec translocon and a translating ribosome

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B5)		28S rRNApolymer48081557519.51GenBank (GBCN01009604.1)Oryctolagus cuniculus (rabbit)
2B
(B7)		5S rRNApolymer12038691.91GenBank (4CXE_4)Oryctolagus cuniculus (rabbit)
3C
(B8)		5.8S rRNApolymer15850809.01GenBank (GBCN01009604.1)Oryctolagus cuniculus (rabbit)
4D
(BA)		60S ribosomal protein L8polymer25728103.91UniProt (A0A5F9C4D3)
UniProt (A0A5F9D5B2)
Pfam (PF00181)
Pfam (PF03947)		Oryctolagus cuniculus (rabbit)
5E
(BB)		Ribosomal protein L3polymer40346121.01UniProt (G1TL06)
Pfam (PF00297)		Oryctolagus cuniculus (rabbit)
6F
(BC)		60S ribosomal protein L4polymer41346430.91UniProt (G1SVW5)
Pfam (PF00573)
Pfam (PF14374)		Oryctolagus cuniculus (rabbit)
7G
(BD)		Ribosomal_L18_c domain-containing proteinpolymer29734481.81UniProt (G1SYJ6)
UniProt (by SIFTS) (P19949)		Oryctolagus cuniculus (rabbit)
8H
(BE)		60S ribosomal protein L6polymer29133028.31UniProt (G1SKF7)
Pfam (PF03868)
Pfam (PF01159)		Oryctolagus cuniculus (rabbit)
9I
(BF)		uL30,60S ribosomal protein L7polymer24729201.81UniProt (G1SV32)
Pfam (PF08079)
Pfam (PF00327)		Oryctolagus cuniculus (rabbit)
10J
(BG)		60S ribosomal protein L7apolymer26630061.81UniProt (G1STW0)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
11K
(BH)		60S ribosomal protein L9polymer19221871.41UniProt (G1SWI6)
Pfam (PF00347)		Oryctolagus cuniculus (rabbit)
12L
(BI)		Ribosomal protein L10polymer21424643.11UniProt (B7NZQ2)
Pfam (PF00252)		Oryctolagus cuniculus (rabbit)
13M
(BJ)		Ribosomal protein L11polymer17820288.51UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)		Oryctolagus cuniculus (rabbit)
14N
(BK)		Nascent chainpolymer292486.11Saccharomyces cerevisiae
15O
(BL)		L13polymer21124331.71UniProt (G1TKB3)
Pfam (PF01294)		Oryctolagus cuniculus (rabbit)
16P
(BM)		Ribosomal protein L14polymer21823870.51UniProt (G1SZ12)
Pfam (PF01929)		Oryctolagus cuniculus (rabbit)
17Q
(BN)		Ribosomal protein L15polymer20424207.31UniProt (G1T0C1)
Pfam (PF00827)		Oryctolagus cuniculus (rabbit)
18R
(BO)		60S ribosomal protein L13apolymer20323533.31UniProt (A0A0N8ETI8)
UniProt (by SIFTS) (G1TVS8)		Oryctolagus cuniculus (rabbit)
19S
(BP)		uL22polymer18421444.21UniProt (G1TVT6)
Pfam (PF00237)
UniProt (by SIFTS) (G1SCJ6)		Oryctolagus cuniculus (rabbit)
20T
(BQ)		eL18polymer18821699.71UniProt (F6QKI9)
Pfam (PF17135)
UniProt (by SIFTS) (G1TFE0)		Oryctolagus cuniculus (rabbit)
21U
(BR)		60S ribosomal protein L19polymer19623535.31UniProt (Q3T0W9)
Pfam (PF01280)		Oryctolagus cuniculus (rabbit)eL19
22V
(BS)		60S ribosomal protein L18apolymer17620749.41UniProt (G1TTY7)
Pfam (PF01775)		Oryctolagus cuniculus (rabbit)
23W
(BT)		60S ribosomal protein L21polymer16018610.01UniProt (G1SHQ2)
Pfam (PF01157)		Oryctolagus cuniculus (rabbit)eL21
24X
(BU)		60S ribosomal protein L22polymer12814756.91UniProt (G1TSG1)
Pfam (PF01776)		Oryctolagus cuniculus (rabbit)
25Y
(BV)		Ribosomal protein L23polymer14014892.51UniProt (G1T6D1)
Pfam (PF00238)		Oryctolagus cuniculus (rabbit)
26Z
(BW)		Ribosomal protein L24polymer15717825.11UniProt (G1SE28)
Pfam (PF01246)		Oryctolagus cuniculus (rabbit)
27AA
(BX)		Ribosomal_L23eN domain-containing proteinpolymer15617768.21UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)		Oryctolagus cuniculus (rabbit)uL23
28BA
(BY)		Ribosomal protein L26polymer14517303.41UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)		Oryctolagus cuniculus (rabbit)
29CA
(BZ)		60S ribosomal protein L27polymer13615835.81UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)		Oryctolagus cuniculus (rabbit)
30DA
(Ba)		60S ribosomal protein L27apolymer14816635.61UniProt (G1SNY0)
Pfam (PF00828)		Oryctolagus cuniculus (rabbit)
31EA
(Bb)		60S ribosomal protein L29polymer24526721.71UniProt (G1SGR6)
Pfam (PF01779)		Oryctolagus cuniculus (rabbit)
32FA
(Bc)		eL30polymer11512807.11UniProt (G1TDL2)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
33GA
(Bd)		Ribosomal protein L31polymer12514494.91UniProt (G1SHG0)
Pfam (PF01198)		Oryctolagus cuniculus (rabbit)eL31
34HA
(Be)		eL32polymer13515898.91UniProt (G1U437)
Pfam (PF01655)
UniProt (by SIFTS) (G1TUN8)		Oryctolagus cuniculus (rabbit)
35IA
(Bf)		60S ribosomal protein L35apolymer11012580.81UniProt (G1SF08)
Pfam (PF01247)		Oryctolagus cuniculus (rabbit)eL33
36JA
(Bg)		60S ribosomal protein L34polymer11713326.11UniProt (G1TXG5)
Pfam (PF01199)		Oryctolagus cuniculus (rabbit)
37KA
(Bh)		60S ribosomal protein L35polymer12314566.61UniProt (G1SIT5)
Pfam (PF00831)		Oryctolagus cuniculus (rabbit)uL29
38LA
(Bi)		60S ribosomal protein L36polymer10512263.81UniProt (G1TTQ5)
Pfam (PF01158)		Oryctolagus cuniculus (rabbit)
39MA
(Bj)		Ribosomal protein L37polymer9711111.01UniProt (U3KPD5)
Pfam (PF01907)		Oryctolagus cuniculus (rabbit)
40NA
(Bk)		eL38polymer708238.91UniProt (G1U001)
Pfam (PF01781)		Oryctolagus cuniculus (rabbit)
41OA
(Bl)		eL39polymer516455.81UniProt (G1TTN1)
Pfam (PF00832)
UniProt (by SIFTS) (G1SYU7)		Oryctolagus cuniculus (rabbit)
42PA
(Bm)		Ubiquitinpolymer12814800.51UniProt (P62975)
Pfam (PF00240)		Oryctolagus cuniculus (rabbit)
43QA
(Bo)		eL42polymer10612490.01UniProt (G1U344)
Pfam (PF00935)
UniProt (by SIFTS) (G1T040)		Oryctolagus cuniculus (rabbit)
44RA
(Bp)		eL43polymer9210299.41UniProt (G1SY53)
Pfam (PF01780)		Oryctolagus cuniculus (rabbit)
45SA
(Br)		60S ribosomal protein L28polymer13715844.71UniProt (G1U7L1)
Pfam (PF01778)		Oryctolagus cuniculus (rabbit)
46TA
(Bs)		60S acidic ribosomal protein P0polymer31834380.51UniProt (G1SPK4)
Pfam (PF00428)
Pfam (PF00466)
Pfam (PF17777)		Oryctolagus cuniculus (rabbit)
47UA
(Bt)		Ribosomal protein L12polymer16517847.61UniProt (G1SMR7)
Pfam (PF03946)
Pfam (PF00298)		Oryctolagus cuniculus (rabbit)
48VA
(Bv)		Ribosomal protein uL1polymer21724875.41UniProt (G1SKZ8)
Pfam (PF00687)		Oryctolagus cuniculus (rabbit)
49WA
(SX)		Protein transport protein Sec61 subunit alpha isoform 1polymer47652279.41UniProt (P38377)
Pfam (PF10559)
Pfam (PF00344)		Canis lupus familiaris (dog)Sec61 alpha-1
50XA
(SY)		Protein transport protein Sec61 subunit gammapolymer687752.31UniProt (P60058)
Pfam (PF00584)		Canis lupus familiaris (dog)
51YA
(SZ)		Protein transport protein Sec61 subunit betapolymer969987.51UniProt (P60467)
Pfam (PF03911)		Canis lupus familiaris (dog)
52ZA
(A2)		18S rRNApolymer1870603928.31GenBank (GBCT01000564.1)Oryctolagus cuniculus (rabbit)
53AB
(AA)		40S ribosomal protein S27polymer849480.21UniProt (G1TZ76)
Pfam (PF01667)		Oryctolagus cuniculus (rabbit)
54BB
(AB)		Ribosomal protein S28polymer697855.11UniProt (G1TIB4)
Pfam (PF01200)		Oryctolagus cuniculus (rabbit)
55CB
(AC)		Ribosomal protein S27apolymer15618004.01UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)		Oryctolagus cuniculus (rabbit)
56DB
(AD)		40S ribosomal protein S30polymer13314498.91UniProt (G1T8A2)
Pfam (PF00240)
Pfam (PF04758)		Oryctolagus cuniculus (rabbit)
57EB
(AE)		eS26polymer11513047.51UniProt (A0A2K5LQY6)
Pfam (PF01283)		Oryctolagus cuniculus (rabbit)
58FB
(AF)		RACK1polymer31735115.71UniProt (G1SJB4)
Pfam (PF00400)		Oryctolagus cuniculus (rabbit)
59GB
(AG)		uS14polymer566690.81UniProt (G1U7M4)
Pfam (PF00253)		Oryctolagus cuniculus (rabbit)
60HB
(AH)		mRNApolymer41200.81Oryctolagus cuniculus
61IB
(AT)		P-site tRNApolymer7524106.31Oryctolagus cuniculus
62JB
(AZ)		40S ribosomal protein SApolymer29532970.01UniProt (G1TLT8)
Pfam (PF00318)
Pfam (PF16122)		Oryctolagus cuniculus (rabbit)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
63KB
(Aa)		40S ribosomal protein S3apolymer26430002.11UniProt (G1SS70)
Pfam (PF01015)		Oryctolagus cuniculus (rabbit)
64LB
(Ab)		Ribosomal_S5_C domain-containing protein,40S ribosomal protein S2polymer29331285.41UniProt (A0A5F9D8I1)
UniProt (G1TUT9)
Pfam (PF00333)
Pfam (PF03719)		Oryctolagus cuniculus (rabbit)
65MB
(Ac)		40S ribosomal protein S3polymer28131146.61UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)		Oryctolagus cuniculus (rabbit)uS3
66NB
(Ad)		40S ribosomal protein S4polymer26329654.91UniProt (G1TK17)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)		Oryctolagus cuniculus (rabbit)
67OB
(Ae)		Ribosomal protein S5polymer20422913.51UniProt (G1TFM5)
Pfam (PF00177)		Oryctolagus cuniculus (rabbit)
68PB
(Af)		40S ribosomal protein S6polymer24928751.91UniProt (G1TM55)
Pfam (PF01092)		Oryctolagus cuniculus (rabbit)
69QB
(Ag)		40S ribosomal protein S7polymer43247356.21UniProt (G1SVB0)Oryctolagus cuniculus (rabbit)
70RB
(Ah)		40S ribosomal protein S8polymer20824263.41UniProt (G1TJW1)
Pfam (PF01201)		Oryctolagus cuniculus (rabbit)
71SB
(Ai)		Ribosomal protein S9 (Predicted)polymer19422641.61UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)		Oryctolagus cuniculus (rabbit)
72TB
(Aj)		Ribosomal protein eS10polymer16518933.81UniProt (G1TPV3)
Pfam (PF03501)
UniProt (by SIFTS) (G1T168)		Oryctolagus cuniculus (rabbit)
73UB
(Ak)		40S ribosomal protein S11polymer15818468.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)		Oryctolagus cuniculus (rabbit)
74VB
(Al)		40S ribosomal protein S12polymer13214539.01UniProt (G1SFR8)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
75WB
(Am)		uS15polymer15117259.41UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)		Oryctolagus cuniculus (rabbit)
76XB
(An)		40S ribosomal protein S14polymer15116316.81UniProt (G1U472)
Pfam (PF00411)
UniProt (by SIFTS) (G1T1F0)		Oryctolagus cuniculus (rabbit)
77YB
(Ao)		40S ribosomal protein uS19polymer14517049.21UniProt (G1U0Q2)
Pfam (PF00203)		Oryctolagus cuniculus (rabbit)
78ZB
(Ap)		uS9polymer17219213.51UniProt (G1SGX4)
Pfam (PF00380)		Oryctolagus cuniculus (rabbit)
79AC
(Aq)		40S ribosomal protein eS17polymer13515552.11UniProt (G1TU13)
Pfam (PF00833)		Oryctolagus cuniculus (rabbit)
80BC
(Ar)		40S ribosomal protein S18polymer15217801.81UniProt (G1TPG3)
Pfam (PF00416)		Oryctolagus cuniculus (rabbit)
81CC
(As)		40S ribosomal protein S19polymer14516104.61UniProt (G1TN62)
Pfam (PF01090)		Oryctolagus cuniculus (rabbit)
82DC
(At)		40S ribosomal protein uS10polymer11913398.81UniProt (G1SIZ2)
Pfam (PF00338)		Oryctolagus cuniculus (rabbit)
83EC
(Au)		40S ribosomal protein S21polymer839181.41UniProt (G1TM82)
Pfam (PF01249)		Oryctolagus cuniculus (rabbit)
84FC
(Av)		Ribosomal protein S15apolymer13014865.61UniProt (G1TG89)
Pfam (PF00410)		Oryctolagus cuniculus (rabbit)
85GC
(Aw)		40S ribosomal protein S23polymer14315860.71UniProt (G1SZ47)
Pfam (PF00164)		Oryctolagus cuniculus (rabbit)
86HC
(Ax)		40S ribosomal protein S24polymer13015107.91UniProt (G1T3D8)
Pfam (PF01282)
UniProt (by SIFTS) (A0A5F9D2E6)		Oryctolagus cuniculus (rabbit)
87IC
(Ay)		40S ribosomal protein S25polymer12413645.01UniProt (G1TDB3)
Pfam (PF03297)		Oryctolagus cuniculus (rabbit)
88JC
(Az)		60S ribosomal protein L41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)		Oryctolagus cuniculus (rabbit)
89KC
(TA)		Translocon-associated protein subunit alphapolymer28632002.81UniProt (P16967)
Pfam (PF03896)		Canis lupus familiaris (dog)TRAP-alpha,PGP35,Signal sequence receptor subunit alpha,SSR-alpha
90LC
(TB)		Translocon-associated protein subunit betapolymer18320121.01UniProt (P23438)
Pfam (PF05753)		Canis lupus familiaris (dog)TRAP-beta,Glycoprotein 25H,gp25H,Signal sequence receptor subunit beta,SSR-beta
91MC
(TC)		Signal sequence receptor subunit 3polymer18521090.51UniProt (A0A8P0SDY6)
Pfam (PF07074)
UniProt (by SIFTS) (A0A8C0T6I4)		Canis lupus familiaris (dog)
92NC
(TD)		Translocon-associated protein subunit deltapolymer17318959.51UniProt (A0A8C0NNM2)
Pfam (PF05404)		Canis lupus familiaris (dog)Signal sequence receptor subunit delta
93AD, CD, DD, ED, FD...
(B5, A2, BN)		SPERMIDINEnon-polymer145.230Chemie (SPD)
94BD, YC, YZ
(B5, A2)		SPERMINEnon-polymer202.33Chemie (SPM)
95AAA, ABA, ACA, ADA, AE...
(A2, B5, As, B8, BT...)		MAGNESIUM IONnon-polymer24.3750Chemie (MG)
96BX
(B7)		GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
97PY
(BD)		ACETYLAMINO-ACETIC ACIDnon-polymer117.11Chemie (AAC)
98IZ, JZ, KGA, LGA, MGA...
(Bg, Bj, AC, AE, AG...)		ZINC IONnon-polymer65.48Chemie (ZN)
Sequence modifications
B5: 1 - 4808 (GenBank: GBCN01009604.1)
PDBExternal DatabaseDetails
Uy1 3550U 5943conflict
BA: 1 - 205 (UniProt: A0A5F9C4D3)
BA: 206 - 257 (UniProt: A0A5F9D5B2)
BF: 1 - 5 (PDB: 8BTK)
BF: 6 - 247 (UniProt: G1SV32)
BG: 1 - 24 (PDB: 8BTK)
BG: 25 - 266 (UniProt: G1STW0)
PDBExternal DatabaseDetails
Ala 86Val 139conflict
Gly 191Cys 244conflict
BL: 1 - 211 (UniProt: G1TKB3)
PDBExternal DatabaseDetails
Arg 74His 74conflict
Arg 190His 190conflict
BO: 1 - 203 (UniProt: A0A0N8ETI8)
PDBExternal DatabaseDetails
Leu 174Ile 174conflict
Asp 194Glu 194conflict
BQ: 1 - 188 (UniProt: F6QKI9)
PDBExternal DatabaseDetails
Arg 134Cys 134conflict
BS: 1 - 175 (UniProt: G1TTY7)
PDBExternal DatabaseDetails
Met 1Thr 1conflict
Pro 18-insertion
Thr 19-insertion
Pro 20Ser 18conflict
Ser 49Leu 47conflict
Gln 50Glu 48conflict
Arg 95His 93conflict
Thr 101Ile 99conflict
Thr 102Met 100conflict
Gly 104Ser 102conflict
Arg 138Pro 136conflict
Ser 168Tyr 166conflict
BS: 176 - 176 (PDB: 8BTK)
BU: 1 - 128 (UniProt: G1TSG1)
PDBExternal DatabaseDetails
Gly 32Arg 32conflict
Ala 36Glu 36conflict
Phe 39Ser 39conflict
Gly 54Arg 54conflict
Arg 97His 97conflict
Bk: 1 - 70 (UniProt: G1U001)
PDBExternal DatabaseDetails
Lys 24Asn 24conflict
Bm: 1 - 76 (UniProt: P62975)
Bm: 77 - 128 (PDB: 8BTK)
Br: 1 - 137 (UniProt: G1U7L1)
PDBExternal DatabaseDetails
Arg 103His 103conflict
A2: 1 - 1870 (GenBank: GBCT01000564.1)
PDBExternal DatabaseDetails
B8n 1249C 3623conflict
4ac 1338C 3712conflict
4ac 1843C 4217conflict
Ab: 1 - 42 (UniProt: A0A5F9D8I1)
PDBExternal DatabaseDetails
Ala 2Val 2conflict
Arg 36Cys 36conflict
Arg 38Gly 38conflict
Gly 39Lys 39conflict
Arg 40Ala 40conflict
Arg 42Asp 42conflict
Ab: 43 - 293 (UniProt: G1TUT9)
PDBExternal DatabaseDetails
Met 73Val 50conflict
Gly 119Ala 96conflict
Arg 194His 171conflict
Met 215Leu 192conflict
Arg 227Trp 204conflict
Gly 228Ser 205conflict
Ad: 1 - 263 (UniProt: G1TK17)
PDBExternal DatabaseDetails
Gly 25Ser 25conflict
Arg 51Lys 51conflict
Thr 78Ala 78conflict
Val 156Met 156conflict
Ah: 1 - 208 (UniProt: G1TJW1)
PDBExternal DatabaseDetails
Arg 47Gly 47conflict
An: 1 - 151 (UniProt: G1U472)
PDBExternal DatabaseDetails
5f0 138Asp 155conflict
As: 1 - 145 (UniProt: G1TN62)
PDBExternal DatabaseDetails
Gly 119Trp 119conflict
Asn 142Lys 142conflict
Au: 1 - 57 (UniProt: G1TM82)
PDBExternal DatabaseDetails
Asn 3Ser 26conflict
Asp 4Asn 27conflict
Gln 33Pro 56conflict
Phe 50Ser 73conflict
Au: 58 - 83 (PDB: 8BTK)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains92
Total formula weight4013619.3
Non-Polymers*Number of molecules793
Total formula weight24356.7
All*Total formula weight4037976.0
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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