8BST
Crystal structure of the kainate receptor GluK3-H523A ligand binding domain in complex with kainate at 2.7A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor ionotropic, kainate 3 | polymer | 258 | 29025.4 | 4 | UniProt (P42264) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluK3,Glutamate receptor 7,GluR-7,GluR7 |
| 2 | E, F, IA, QA, RA... (A, C, D, B) | ACETATE ION | non-polymer | 59.0 | 6 | Chemie (ACT) | |||
| 3 | G, H, I, J, JA... (A, C, D, B) | ZINC ION | non-polymer | 65.4 | 13 | Chemie (ZN) | |||
| 4 | AA, BA, K, L, LA... (B, A, C, D) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 5 | CA, DA, M, MA, N... (B, A, C, D) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 6 | Q (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | EA, PA, R, WA (B, C, A, D) | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 4 | Chemie (KAI) | |||
| 8 | FA, GA, HA, S, XA (B, A, D) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 9 | AB, BB, YA, ZA (C, D, A, B) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 432 - 546 (UniProt: P42264)
A, B, C, D: 669 - 806 (UniProt: P42264)
| PDB | External Database | Details |
|---|---|---|
| Gly 429 | - | expression tag |
| Pro 430 | - | expression tag |
| Gly 431 | - | expression tag |
| Ala 523 | His 523 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 547 | - | linker |
| Thr 548 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116101.5 | |
| Non-Polymers* | Number of molecules | 46 |
| Total formula weight | 3832.9 | |
| All* | Total formula weight | 119934.4 |
