8BSL
Human GLS in complex with compound 12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutaminase kidney isoform, mitochondrial | polymer | 478 | 53227.9 | 4 | UniProt (O94925) Pfam (PF17959) Pfam (PF04960) | Homo sapiens (human) | GLS,K-glutaminase,L-glutamine amidohydrolase |
| 2 | E, F (A, D) | ~{N}-[5-[[(3~{R})-1-(5-azanyl-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]-2-phenyl-ethanamide | non-polymer | 402.5 | 2 | Chemie (R90) | |||
| 3 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 771 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 123 - 598 (UniProt: O94925)
| PDB | External Database | Details |
|---|---|---|
| Gly 121 | - | expression tag |
| Ser 122 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 212911.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 805.0 | |
| All* | Total formula weight | 213716.5 |
