Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | Interleukin-1 receptor-associated kinase 4 | polymer | 298 | 33286.6 | 2 | UniProt (Q9NWZ3) Pfam (PF07714) | Homo sapiens (human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 2 | C, D (AAA, BBB) | ~{N}-[6-methoxy-2-(2-methylsulfonylethyl)-1,3-dihydroindazol-5-yl]-6-(2-oxidanylpropan-2-yl)pyridine-2-carboxamide | non-polymer | 434.5 | 2 | Chemie (R6I) | |||
| 3 | E (BBB) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | F, G (AAA, BBB) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 165 - 460 (UniProt: Q9NWZ3)
| PDB | External Database | Details |
|---|---|---|
| Gly 163 | - | expression tag |
| Ser 164 | - | expression tag |
| Ala 400 | Lys 400 | engineered mutation |
| Ala 401 | Glu 401 | engineered mutation |
| Ala 402 | Glu 402 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66573.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 928.1 | |
| All* | Total formula weight | 67501.2 |
